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Different Manifestations Across Patients
Type 2 Inflammation May Be A Clear Connection

Type 2 inflammation is characterized by immune dysregulation and epithelial barrier dysfunction—both provide evidence of Type 2 pathway activation in disease1,2

CRS, chronic rhinosinusitis; EOS, eosinophil; FeNO, fractional exhaled nitric oxide; ILC2, type 2 innate lymphoid cell.

  1. Gandhi NA, Bennett BL, Graham NMH, Pirozzi G, Stahl N, Yancopoulos GD. Targeting key proximal drivers of type 2 inflammation in disease. Nat Rev Drug Discov. 2016;15(1):35-50.
  2. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, 2020. Accessed October 28, 2020. https://ginasthma.org/wp-content/uploads/2020/06/GINA-2020-report_20_06_04-1-wms.pdf

Watch how Type 2 inflammation can affect
a range of patients1

Atopic Dermatitis
Asthma
Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP)
Eosinophilic Esophagitis (EoE)

Watch how Type 2 Inflammation can affect
a range of patients1

Type 2 Inflammation
Atopic Dermatitis
Asthma
Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP)
Eosinophilic Esophagitis (EoE)

Watch how Type 2 Inflammation can affect
a range of patients1

Watch how Type 2 Inflammation can affect
a range of patients1

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INDICATIONS

CRS, chronic rhinosinusitis; EOS, eosinophil; FeNO, fractional exhaled nitric oxide; ILC2, type 2 innate lymphoid cell.

  1. Gandhi NA, Bennett BL, Graham NMH, Pirozzi G, Stahl N, Yancopoulos GD. Targeting key proximal drivers of type 2 inflammation in disease. Nat Rev Drug Discov. 2016;15(1):35-50.
  2. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, 2020. Accessed October 28, 2020. https://ginasthma.org/wp-content/uploads/2020/06/GINA-2020-report_20_06_04-1-wms.pdf