Printed From:

A SIGNIFICANT UNMET MEDICAL
NEED REMAINS FOR MANY
PATIENTS WITH EoE1

Current standard-of-care therapies for EoE do not fully address Type 2 inflammation2-4

Elimination
diet

Proton pump
inhibitors

Swallowed topical
corticosteroids

Esophageal
dilation

Repeat endoscopies, including those used to establish proper diet, are associated with procedure-related complications and high costs5,6

There remains an unmet need to reduce esophageal dysfunction and
eosinophil-predominant inflammation in order to improve endoscopic
signs, clinical symptoms, and quality of life in patients with EoE1

EoE, eosinophilic esophagitis.

References: 1. Lucendo AJ, Molina-Infante J, Arias Á, et al. Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults. United European Gastroenterol J. 2017;5(3):335-358. 2. O’Shea KM, Aceves SS, Dellon ES, et al. Pathophysiology of eosinophilic esophagitis. Gastroenterology. 2018;154(2):333-345. 3. Wolf WA, Dellon ES. Eosinophilic esophagitis and proton pump inhibitors: controversies and implications for clinical practice. Gastroenterol Hepatol (N Y). 2014;10(7):427-432. 4. D’Alessandro A, Esposito D, Pesce M, Cuomo R, De Palma GD, Sarnelli G. Eosinophilic esophagitis: from pathophysiology to treatment. World J Gastrointest Pathophysiol. 2015;6(4):150-158. 5. Watts A, Alexander JA, Gupta SK. Eosinophilic esophagitis: search for non-invasive techniques for long-term monitoring. Gastrointest Endosc. 2016;83(2):307-308. 6. Baker RD, Baker SS. Towards better diagnosis and monitoring of eosinophilic esophagitis: are we there yet? J Pediatr Gastroenterol Nutr. 2020;70(4):410.