See the Type 2 inflammatory
pathway in action for:
* IL-4 drives differentiation of naive CD4(+) T cells to Th2.
CRSwNP, chronic rhinosinusitis with nasal polyposis; CSU, chronic spontaneous urticaria; EoE, eosinophilic esophagitis; FcεR1, high-affinity IgE receptor; ILC2, type 2 innate lymphoid cell; PN, prurigo nodularis; TSLP, thymic stromal lymphopoietin.
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3. Gittler JK, Shemer A, Suárez-Fariñas M, et al. Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis.
J Allergy Clin Immunol. 2012;130(6):1344-1354.
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of Allergy, Asthma & Immunology. J Allergy Clin lmmunol. 2013;131(6):1479-1490.
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